Human FFPE Tissue Samples
Formalin-fixed paraffin-embedded (FFPE) human tissue samples are the golden standard for histologic analysis of surgically removed tissues and a critical source for biomedical research.
Oncology: Breast, Prostate, Liver, Lung, Normal Adjacent Tissue (NAT)
Rheumatology: Synovium
Dermatology: skin cancer tissue (basal cell carcinoma, squamous cell carcinoma, melanoma), psoriasis lesions
Tissue Collection
We ensure that the patient’s safety, wellbeing and comprehensive diagnosis are protected by complying with all local and international ethical regulations.
We understand the great value of FFPEs, but we also recognize the elevated variability in their processing techniques, often leading to inconclusive results.
Our FFPE tissue specimens are collected under IRB approval and prepared in strict accordance with our established processing protocols.
Nevertheless, we adapt to our clients’ specific needs. Any step of the FFPE preparation can be customized to fit your study’s design.
FFPE Tissue Formats
Unless specifically requested, our collections are composed by standard sized FFPEs of 1x1x0.5cm allowing the generation of at least 200 x 4-5µm cuts. All FFPE tumor tissues have high tumor content and low necrosis. Variations in these parameters could occur based on the nature of the disease, tissue type and tumor heterogeneity.
Each FFPE block is accompanied by detailed clinical information and pathological data.
quality control (H&E staining) is performed on 100% of FFPE samples by a pathologist.
Laboratory Services for FFPE Tissue
Upon request, Medicalit Gate Bioscience can provide additional testing of FFPE blocks which include:
Extended pathology review with a description of the requested features of the tissue
Preparation of stained/non-stained histological slides (regular and adhesive slides)
Preparation of serial tissue sections
Preparation of tissue curls/scrolls
Digital pathology images of micro specimens
Immunohistochemical testing of different levels of complexity
Molecular-genetic analysis (FISH method)
Gene mutation analysis by PCR or NGS
Flow cytometry
Shipping of FFPE Tissues
Our FFPE tissue samples are stored and shipped at room temperature.
We take extra care when organizing our shipments to ensure that your FFPE samples will arrive to you at their best condition.
We are committed to organizing your collections and delivering your samples in the most convenient manner for you and we take into account any specific requirements you might have.
